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Burkhard Becher Selected Research

Inflammation (Inflammations)

1/2024GM-CSF-mediated epithelial-immune cell crosstalk orchestrates pulmonary immunity to Aspergillus fumigatus.
12/2023Cell-binding IgM in CSF is distinctive of multiple sclerosis and targets the iron transporter SCARA5.
10/2023IL-12 sensing in neurons induces neuroprotective CNS tissue adaptation and attenuates neuroinflammation in mice.
7/2023A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation.
1/2023S100A9 Drives the Chronification of Psoriasiform Inflammation by Inducing IL-23/Type 3 Immunity.
10/2021IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation.
1/2021GM-CSF instigates a dendritic cell-T-cell inflammatory circuit that drives chronic asthma development.
1/2021GM-CSF: Master regulator of the T cell-phagocyte interface during inflammation.
1/2020Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1.
1/2020The AP1 Transcription Factor Fosl2 Promotes Systemic Autoimmunity and Inflammation by Repressing Treg Development.
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Burkhard Becher Research Topics

Disease

45Inflammation (Inflammations)
01/2024 - 08/2002
19Neoplasms (Cancer)
02/2024 - 11/2010
19Multiple Sclerosis
12/2023 - 08/2002
18Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2024 - 08/2002
14Neuroinflammatory Diseases
10/2023 - 02/2008
10Autoimmune Diseases (Autoimmune Disease)
01/2021 - 08/2002
9Infections
01/2024 - 07/2011
8Psoriasis (Pustulosis Palmaris et Plantaris)
10/2021 - 06/2012
6Colitis
06/2021 - 01/2009
5Brain Neoplasms (Brain Tumor)
11/2023 - 01/2020
5Demyelinating Diseases (Demyelinating Disease)
01/2023 - 12/2006
5Leukemia
01/2022 - 01/2018
5Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
06/2021 - 08/2012
5Atherosclerosis
01/2020 - 11/2004
3Pneumonia (Pneumonitis)
04/2024 - 01/2020
3Graft vs Host Disease (Graft-Versus-Host Disease)
01/2024 - 11/2018
3Melanoma (Melanoma, Malignant)
10/2023 - 01/2018
3Myasthenia Gravis
01/2023 - 01/2021
3COVID-19
01/2023 - 01/2020
3Glioma (Gliomas)
01/2023 - 12/2013
3Glioblastoma (Glioblastoma Multiforme)
01/2023 - 01/2020
3Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2022 - 01/2018
3Neoplasm Metastasis (Metastasis)
01/2021 - 12/2017
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2024 - 10/2023
2Necrosis
01/2023 - 10/2011
2Asthma (Bronchial Asthma)
01/2021 - 08/2011
2Lung Diseases (Lung Disease)
01/2021 - 01/2011
2Respiratory Hypersensitivity
01/2021 - 08/2011
2Sepsis (Septicemia)
10/2019 - 01/2019
2Autoimmune Diseases of the Nervous System
01/2019 - 08/2002
2Narcolepsy
10/2018 - 11/2016
2Sleep Wake Disorders
10/2018 - 11/2016
2Central Nervous System Diseases (CNS Diseases)
01/2018 - 01/2009
2Alzheimer Disease (Alzheimer's Disease)
06/2015 - 12/2012
1Mycoses (Diseases, Fungus)
01/2024
1Disease Progression
12/2023
1Head and Neck Neoplasms (Head and Neck Cancer)
11/2023

Drug/Important Bio-Agent (IBA)

32CytokinesIBA
02/2024 - 08/2002
23Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
01/2024 - 06/2011
16Interleukin-23 (Interleukin 23)IBA
02/2024 - 10/2003
15Interleukin-12 (IL 12)IBA
10/2023 - 08/2002
9Interleukin-17 (Interleukin 17)IBA
09/2023 - 10/2007
8AntigensIBA
01/2021 - 03/2005
6Immune Checkpoint InhibitorsIBA
04/2024 - 01/2018
6AntibodiesIBA
04/2024 - 01/2008
6Imiquimod (Aldara)FDA LinkGeneric
01/2023 - 06/2012
6Interleukin-22 (IL-22)IBA
12/2018 - 10/2007
5Biomarkers (Surrogate Marker)IBA
04/2024 - 12/2011
5InterferonsIBA
01/2022 - 06/2010
5InterleukinsIBA
01/2021 - 09/2006
4Proteins (Proteins, Gene)FDA Link
04/2024 - 09/2015
4Interleukin-15 (Interleukin 15)IBA
01/2023 - 01/2018
3AutoantibodiesIBA
04/2024 - 12/2006
3RNA (Ribonucleic Acid)IBA
10/2023 - 01/2020
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2023 - 06/2010
3LigandsIBA
01/2022 - 09/2006
3Peptides (Polypeptides)IBA
01/2021 - 01/2019
3chenodeoxycholate sulfate conjugate (CDCS)IBA
01/2021 - 06/2013
3Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2021 - 11/2016
3Transcription Factors (Transcription Factor)IBA
01/2020 - 01/2009
3Interleukin-2 (IL2)IBA
01/2019 - 11/2015
2Surface-Active Agents (Surfactants)IBA
04/2024 - 01/2024
2Macrophage Colony-Stimulating FactorIBA
01/2023 - 12/2012
2Cholinergic ReceptorsIBA
01/2023 - 01/2021
2VaccinesIBA
01/2023 - 07/2011
2Messenger RNA (mRNA)IBA
01/2023 - 11/2017
2Dimethyl FumarateIBA
01/2022 - 01/2022
2AutoantigensIBA
01/2022 - 08/2007
2Clodronic Acid (Clodronate)IBA
06/2021 - 01/2021
2Fc Receptors (Fc Receptor)IBA
01/2021 - 12/2006
2Interleukin-10 (Interleukin 10)IBA
01/2021 - 08/2015
2Toll-Like Receptors (Toll-Like Receptor)IBA
01/2021 - 06/2013
2LipidsIBA
01/2020 - 11/2004
2Scavenger Receptors (Scavenger Receptor)IBA
01/2020 - 11/2004
2Anti-Bacterial Agents (Antibiotics)IBA
10/2019 - 08/2011
2OrexinsIBA
10/2018 - 11/2016
2HLA-DQB1 antigen (HLA DQB1)IBA
10/2018 - 11/2016
2Sorafenib (BAY 43-9006)FDA Link
04/2018 - 01/2018
2Diphtheria ToxinIBA
06/2015 - 04/2015
2Amyloid (Amyloid Fibrils)IBA
06/2015 - 12/2012
2Interleukin-18 (Interleukin 18)IBA
04/2015 - 09/2006
2oxidized low density lipoproteinIBA
10/2014 - 05/2010
2Apolipoproteins E (ApoE)IBA
10/2014 - 11/2004
2AllergensIBA
08/2011 - 01/2011
1Interferon-gamma (Interferon, gamma)IBA
04/2024
1Immunoglobulin G (IgG)IBA
04/2024
1IgA receptor (protein B)IBA
04/2024
1Adrenal Cortex Hormones (Corticosteroids)IBA
01/2024
1Interferon LambdaIBA
01/2024
1Interleukin-1 (Interleukin 1)IBA
01/2024
1Protein CIBA
01/2024
1Complement System Proteins (Complement)IBA
12/2023
1IronIBA
12/2023
1Immunoglobulin M (IgM)IBA
12/2023
1Surface Antigens (Surface Antigen)IBA
12/2023

Therapy/Procedure

19Therapeutics
04/2024 - 01/2009
9Immunotherapy
11/2023 - 11/2015
4Cell Transplantation
01/2022 - 01/2018
1Spinal Injections
01/2024
1Radiotherapy
11/2023